原推:Predicting protein structure (a la alphafold) is an on-the-way step to figuring out how to develop treatment.
Here the authors use AI to solve the next step: generating the antibody that will puzzle-piece into the known protein structure.
A very cool paper. https://t.co/e27FoaRTx7
We show that generative AI + high-throughput wet lab experimentation are a powerful combo that enable de novo antibody design. We validate hundreds of AI-designed antibodies and open source this data:
Paper: biorxiv.org/content/10.110…
Data: github.com/AbSciBio/unloc… twitter.com/abscibio/statu…